Each capsule contains: Wild Blueberry fruit (vaccinium angustifolium, anthocyanin extract) 375 mg • VitaBlue brand Wild Blueberry 130-150:1 fruit extract (vaccinium angustifolium) 75 mg • AuroraBlue brand Wildcrafted Blueberry extract complex 50 mg: Vaccinium ovalifolium sm (Alaska early blueberry), Alaska Black Huckleberry (vaccinium alaskaense how.), Alpine Blueberry (vaccinium uliginosum L. spp. alpinum [Bigel. Hult.]), Bog Bilberry (vaccinium uliginosum L. spp. mycrophyllum lange). Other Ingredients: Vegetable Cellulose (capsule), Rice Flour, Silica, Vegetable Stearate.
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Below is general information about the effectiveness of the known ingredients contained in the product Blueberry Extract Capsules. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
INSUFFICIENT RELIABLE EVIDENCE to RATE
INSUFFICIENT RELIABLE EVIDENCE to RATE
Below is general information about the safety of the known ingredients contained in the product Blueberry Extract Capsules. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
LIKELY SAFE ...when used orally and appropriately. Blueberry, as the whole fruit, juice, or in a powder formulation, is safe when consumed in amounts commonly found in foods (13533,92387,92388,92394,96467,97181,99139). There is insufficient reliable information available about the safety of blueberry when used topically or when the leaves are used orally.
CHILDREN: LIKELY SAFE
when used orally and appropriately in amounts commonly found in foods (13533,96465).
PREGNANCY AND LACTATION: LIKELY SAFE
when used orally in amounts commonly found in foods (13533,107281).
There is insufficient reliable information available about the safety of blueberry for medicinal use; avoid using.
POSSIBLY SAFE ...when the fruit is used orally in food amounts (96816).
POSSIBLY UNSAFE ...when fungus-infested plants are used orally in large amounts. Poisoning has been reported when individuals ingest fruit from fungus-infested plants (18). There is insufficient reliable information available about the safety of bog bilberry fruit when used orally in medicinal amounts.
PREGNANCY AND LACTATION: POSSIBLY SAFE
when the fruit is used orally in food amounts (96816).
PREGNANCY AND LACTATION: POSSIBLY UNSAFE
when fungus-infested plants are used orally in large amounts; avoid using (18).
There is insufficient reliable information available about the safety of bog bilberry when used orally in medicinal amounts.
Below is general information about the interactions of the known ingredients contained in the product Blueberry Extract Capsules. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Theoretically, blueberries or blueberry leaf extracts might increase the risk of hypoglycemia when taken with antidiabetes drugs.
 Details
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Theoretically, blueberry juice might increase blood levels of buspirone.
Details
In vitro research shows that blueberry juice can inhibit the metabolism of buspirone, possibly by inhibiting cytochrome P450 3A (CYP3A) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking buspirone hydrochloride 10 mg does not significantly affect the concentration or clearance of buspirone (92385).
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Theoretically, blueberry juice might increase blood levels of flurbiprofen.
Details
In vitro research shows that blueberry juice can inhibit the metabolism of flurbiprofen, possibly by inhibiting cytochrome P450 2C9 (CYP2C9) enzymes. However, pharmacokinetic research in humans shows that drinking 300 mL of blueberry juice 30 minutes before taking flurbiprofen 100 mg does not significantly affect the concentration or clearance of flurbiprofen (92385).
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Below is general information about the adverse effects of the known ingredients contained in the product Blueberry Extract Capsules. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General
...Orally, blueberry is generally well tolerated.
Most Common Adverse Effects:
Orally: Constipation, diarrhea, nausea, and vomiting with freeze-dried blueberries.
Gastrointestinal ...Orally, freeze-dried blueberries may cause constipation, diarrhea, nausea, and vomiting. In one clinical trial, 26% of patients taking freeze-dried blueberries 50 grams daily dropped out in the first week of the study due to gastrointestinal complaints (107278).
General ...Bog bilberry fruit seems to be generally well tolerated when consumed in the amounts found in food. There is a limited amount of information available about the safety of bog bilberry fruit when used orally in medicinal amounts.
Gastrointestinal ...Orally, poisonings from the ingestion of large quantities of the bog bilberry fruit are rare and were thought to be due to contamination with a fungus, Sclerroyina megalospora, that sometimes grows on bog bilberry (18). The symptoms of poisoning include queasiness and vomiting (18).
Neurologic/CNS ...Orally, poisonings from the ingestion of large quantities of the bog bilberry fruit are rare and were thought to be due to contamination with a fungus, Sclerroyina megalospora, that sometimes grows on bog bilberry (18). The symptoms of poisoning include states of intoxication, feelings of weakness, and visual disorders (18).
