Yin Chen Hao [Discontinued] by Hawaii Pharm

INSUFFICIENT RELIABLE EVIDENCE to RATE

• Asthma. Although there has been interest in using oral yin chen for asthma, there is insufficient reliable information about the clinical effects of yin chen for this condition.
• Biliary disorders. Although there has been interest in using oral yin chen for biliary disorders, there is insufficient reliable information about the clinical effects of yin chen for this condition.
• Dysmenorrhea. Although there has been interest in using oral yin chen for dysmenorrhea, there is insufficient reliable information about the clinical effects of yin chen for this condition.
• Liver disease. Although there has been interest in using oral yin chen for liver disease, there is insufficient reliable information about the clinical effects of yin chen for this condition.
• Metabolic syndrome. Although there has been interest in using oral yin chen for metabolic syndrome, there is insufficient reliable information about the clinical effects of yin chen for this condition.
• Neonatal jaundice. Although there has been interest in using intravenous yin chen for neonatal jaundice, there is insufficient reliable information about the clinical effects of yin chen for this condition. More evidence is needed to rate yin chen for these uses.

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POSSIBLY SAFE ...when the above ground parts are used orally and appropriately (12,4342).

POSSIBLY UNSAFE ...when the above ground parts are used orally in doses of 15 grams or more (12). High doses have been reported to cause numbness and tremor of the upper extremities, arrhythmias, and fainting (12).

PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.

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CNS DEPRESSANTS Interaction Rating = Moderate Be cautious with this combination. Severity = Moderate •  Occurrence = Possible •  Level of Evidence = D Theoretically, yin chen might enhance the therapeutic and adverse effects of other CNS depressants.  Details Animal research shows that yin chen has sedative effects and can reduce motor activity and impair balance and coordination. When used in combination with pentobarbital, yin chen increases sleeping time when compared to pentobarbital alone (97859).

PENTOBARBITAL (Nembutal) Interaction Rating = Moderate Be cautious with this combination. Severity = High •  Occurrence = Possible •  Level of Evidence = D Theoretically, yin chen might enhance the therapeutic and adverse effects of pentobarbital.  Details Animal research shows that yin chen, given orally in combination with pentobarbital, can increase sleeping time compared to pentobarbital alone (97859).

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General ...Orally, yin chen seems to be generally well tolerated.
Most Common Adverse Effects:
Abdominal distension, dizziness, nausea.
Serious Adverse Effects (Rare):
Cardiac arrhythmias, fainting, numbness, tremors.

Cardiovascular ...Orally, taking yin chen in doses of 15-30 grams has been reported to cause arrhythmias (12). In one study, two females taking yin chen and da zao (Fructus Zizyphi Jujubae) orally to treat infectious hepatitis developed Adams-Stokes syndrome (sudden collapse into unconsciousness due to serious arrhythmias). It is not clear if yin chen, da zao, the combination, or another factor was responsible (4342).

Gastrointestinal ...Orally, yin chen has been reported to cause nausea and abdominal distention (4343).

Neurologic/CNS ...Orally, yin chen has been reported to cause dizziness (4343). Taking yin chen in doses of 15-30 grams has been reported to cause headache, numbness and tremor of the upper extremities, and fainting (12).

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