Ban Lan Gen Alcohol Free by Hawaii Pharm

POSSIBLY EFFECTIVE

• Psoriasis. Clinical research shows that topical isatis leaf extract may reduce the severity of nail psoriasis. Details: A small clinical study in patients with fingernail psoriasis shows that using a specific product containing indigo naturalis, an isatis leaf extract, in olive oil (Lindioil), 0.05-0.1 mL topically to nail folds and to skin beneath the edge of the nail twice daily for 24 weeks, improves fingernail psoriasis severity by 50% to 80% when compared with treatment with a solution containing calcipotriol (Daivonex scalp solution) 50 mcg/mL (88276). Another small clinical study in this population shows that applying 0.05 mL of this same product to the fingernails twice daily for 12 weeks improves fingernail psoriasis severity by 50% to 59%, compared with 16% to 23% in those using the olive oil vehicle as a control (108089).

INSUFFICIENT RELIABLE EVIDENCE to RATE

• Aging skin. It is unclear if topical isatis can improve the appearance of aging skin. Details: A small clinical study in healthy females aged 37-59 years shows that twice daily facial application of a cream containing isatis leaf extract for 8 weeks improves the visual appearance of wrinkles and roughness scores when compared with baseline (108088). It is unclear if the improvement from baseline differed between those receiving the isatis leaf extract cream and those receiving a placebo cream.
• Diarrhea. Although there is interest in using oral isatis for diarrhea, there is insufficient reliable information about the clinical effects of isatis for this condition.
• Hepatitis. Although there is interest in using oral isatis for hepatitis, there is insufficient reliable information about the clinical effects of isatis for this condition.
• Prostate cancer. Although there is interest in using oral isatis for the treatment of prostate cancer, there is insufficient reliable information about the clinical effects of isatis for this purpose.
• Respiratory tract infections. Although there is interest in using oral isatis for respiratory tract infections, there is insufficient reliable information about the clinical effects of isatis for this purpose.
• Ulcerative colitis. Although there is interest in using oral isatis for ulcerative colitis, there is insufficient reliable information about the clinical effects of isatis for this condition. More evidence is needed to rate isatis for these uses.

(Read more about ISATIS)

POSSIBLY SAFE ...when used topically and appropriately, short-term. A specific product containing indigo naturalis, an isatis leaf extract, in olive oil (Lindioil), applied topically in doses of 0.05-0.1 mL to the skin around the fingernails twice daily, has been used with apparent safety for 24 weeks (88276,108089). There is insufficient reliable information available about the safety of isatis when used orally.

PREGNANCY AND LACTATION:
Insufficient reliable information is available; avoid using.

(Read more about ISATIS)

(Read more about ISATIS)

General ...Orally and topically, no adverse effects have been reported. However, a thorough evaluation of safety outcomes has not been conducted.

(Read more about ISATIS)